IVF Centre · Nagpur
Advanced IVF treatment with a 65%+ success rate — personalised protocols, state-of-the-art embryology lab and compassionate care led by Dr. Rasika Pise Gulhane, FNB Reproductive Medicine.
Understanding IVF
In Vitro Fertilisation (IVF) — commonly called the "test tube baby" procedure — is the gold-standard assisted reproductive technology in which eggs are retrieved from the ovaries, fertilised with sperm in our laboratory, and the resulting embryo is transferred directly into the uterus. IVF bypasses the fallopian tubes entirely, making it effective for a wide range of fertility diagnoses.
IVF is far more common than most people realise. Globally, 1 in 6 couples experience difficulty conceiving at some point. At Medigrace Hospital, our IVF programme has delivered 500+ successful cycles with a clinical pregnancy rate of 65%+, consistently outperforming the national average.
IVF at Medigrace — At a Glance
Duration of one cycle
4–6 weeks from stimulation start to pregnancy test
Egg retrieval
Under IV sedation — painless, day-procedure
Fertilisation
Standard IVF or ICSI — decided on embryologist advice
Embryo culture
3–5 days; blastocyst culture preferred (Day 5)
Embryo transfer
Single best embryo (eSET) for safety and quality
Surplus embryos
Vitrified (frozen) for future FET cycles
Pregnancy test
Beta-hCG blood test 10–14 days post-transfer
The IVF Journey
Every IVF cycle at Medigrace follows a rigorously monitored, internationally benchmarked protocol. Here is exactly what to expect — step by step.
Daily hormonal injections (FSH/LH analogues) stimulate the ovaries to produce multiple mature follicles. Monitoring scans and blood tests every 2–3 days allow precise dose adjustments to maximise egg yield while minimising OHSS risk.
Under intravenous sedation (you are asleep and pain-free), mature eggs are aspirated from follicles via a fine ultrasound-guided needle through the vaginal wall. The procedure takes 15–20 minutes and most patients return home the same day.
A semen sample is collected on the day of egg retrieval. Sperm is then washed and prepared to isolate the healthiest, most motile cells. When necessary, TESA/PESA surgical retrieval is performed prior to this step.
Eggs are placed with prepared sperm in our ISO-standard embryology lab for conventional IVF fertilisation, or a single sperm is injected directly into each egg (ICSI) when sperm quality is a concern. Fertilisation is confirmed 16–18 hours later.
Fertilised embryos are cultured in optimised incubators for 3–5 days. Our embryologists grade each embryo daily. We aim to develop embryos to the blastocyst stage (Day 5) as blastocysts have higher implantation potential.
The highest-graded embryo is loaded into a fine, soft catheter and gently placed into the uterine cavity under ultrasound guidance. The procedure is painless, takes about 10 minutes, and no anaesthesia is required. Surplus embryos are vitrified (frozen).
After embryo transfer, progesterone supplementation (pessaries or injections) is prescribed to support endometrial receptivity and early embryo development. This critical phase lasts until your pregnancy blood test and beyond if positive.
A serum beta-hCG blood test is performed 10–14 days after embryo transfer. A rising hCG level confirms implantation. An ultrasound scan 2 weeks later checks for the heartbeat and number of sacs. Our team is with you every step of the way.
Indications
IVF is recommended across a wide range of diagnoses. Here are the six main groups of patients who benefit most from IVF at Medigrace Hospital.
Women with blocked, damaged or absent fallopian tubes cannot achieve natural conception. IVF completely bypasses the tubes — the egg and sperm meet in our laboratory instead — making it the definitive treatment for tubal infertility.
Polycystic ovary syndrome is the most common cause of ovulatory infertility. When ovulation-induction medications and IUI have failed, IVF with carefully titrated stimulation protocols — tailored to avoid OHSS — delivers excellent results in PCOS patients.
Severe oligospermia (low count), asthenospermia (poor motility) or teratospermia (abnormal shape) reduce the probability of natural fertilisation. IVF combined with ICSI — injecting a single sperm directly into the egg — overcomes most male-factor barriers.
Approximately 30% of couples have no identifiable cause after full investigation. IVF reveals hidden fertilisation failures that basic tests cannot detect, and routinely achieves pregnancy in couples who have tried naturally for several years without success.
Ovarian reserve and egg quality decline with age, particularly after 35. IVF maximises the number of eggs retrieved in a single cycle and allows embryo grading so the best-quality embryo is transferred, improving the chance of success in older patients.
After 3–4 failed IUI cycles or previous failed IVF attempts elsewhere, it is time to reassess. At Medigrace, we review all prior treatment records, investigate potential reasons for failure, and design a fresh protocol — often achieving success where others have not.
Not sure if IVF is right for you?
Book a free consultation with Dr. Rasika Pise Gulhane. After reviewing your investigations, she will advise whether IVF, IUI or another treatment is the best starting point for your situation.
Dr. Rasika Pise Gulhane
MS (OB/GYN) · FMAS · FNB Reproductive Medicine
Why Choose Medigrace
Choosing an IVF centre is one of the most important decisions you will make. Here is why thousands of couples trust Medigrace Hospital for their fertility journey in Nagpur.
Our ISO-compliant embryology laboratory uses Benchtop incubators with time-lapse imaging, tri-gas culture conditions (5% O₂), and vitrification for cryopreservation — the same technology used in top IVF centres globally.
We do not use one-size-fits-all protocols. Every patient's antral follicle count, AMH level, BMI and prior response guides a bespoke stimulation plan — long down-regulation, antagonist, mini-IVF or natural-cycle IVF as appropriate.
Every egg retrieval, fertilisation and transfer at Medigrace is overseen by our senior clinical embryologist. No outsourced lab work. This ensures consistent quality control and direct accountability for every embryo in our care.
Our in-house fertility counsellor supports you through every phase — from treatment preparation and the two-week wait to managing the emotional weight of a failed cycle. Compassionate, confidential, always available.
Our IVF success rate per embryo transfer cycle is 65%+ — significantly above the national average of ~40–45%. This is the result of rigorous patient selection, precise laboratory conditions, and individualised medical protocols.
IVF is as much an emotional journey as a physical one. Our dedicated fertility counsellor is available throughout your treatment — individual sessions, two-week-wait support and, when needed, couples counselling.
What Affects Outcomes
Understanding what influences IVF success helps you make informed decisions and set realistic expectations. Here are the four key factors our team considers.
The single most important factor. A woman under 35 has a significantly higher probability of IVF success than a woman over 40. This is because egg quantity and quality decline with age. We adjust stimulation protocols and set realistic expectations based on age at the first consultation.
Key Stat
Under 35: ~65–70% | 35–37: ~55% | 38–40: ~40% | Over 40: ~20–30%
Embryos are graded on morphology (appearance) at Day 3 and Day 5. A top-grade blastocyst (4AA or 5AA) has an implantation rate of 50–60% per transfer. Our embryologists use international Gardner grading criteria and time-lapse imaging to select the best embryo.
Key Stat
Top-grade blastocyst: 50–60% implantation per transfer
The uterine lining must be at least 8 mm thick, trilaminar in appearance, and receptive at the time of transfer. Conditions like endometrial polyps, fibroids or prior surgery can impair receptivity. We assess and treat all such issues before transfer.
Key Stat
Optimal lining ≥8 mm trilaminar significantly improves implantation
Smoking reduces IVF success rates by up to 50%. Obesity (BMI >30) and being underweight both impair ovarian response. Alcohol, excessive caffeine, and high stress also negatively impact outcomes. We provide targeted lifestyle counselling as part of every treatment plan.
Key Stat
Non-smokers at healthy BMI achieve the best outcomes
All success rate figures are approximate and based on Medigrace Hospital's clinical data and published literature. Individual outcomes vary. Dr. Rasika will provide personalised probability estimates at your consultation.
FAQs
Every success story at Medigrace began with a single consultation. Book yours today — it's free.